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Post was not sent - check your email addresses! At 5 years, it became challenging to identify what the risk factors were, although 1 risk factor that stood out was nail disease at baseline, which was something we already knew. Program and Faculty are updated daily - check back often for the most up-to-date information. - Conference Coverage here. Long-term outcomes with filgotinib, an oral selective Janus kinase 1 inhibitor: 100-week data from an open-label extension (OLE) study in patients with active psoriatic arthritis (PsA). The increasing availability of detailed electronic health record data, along with methods such as machine learning and natural language processing (NLP), provide an opportunity to streamline our ability to find these patients. The American College of Rheumatology’s annual Convergence conference, which took place Nov. 5–9, featured significant contributions from Brigham and Women’s Hospital physicians and scientists. You’ve viewed {{metering-count}} of {{metering-total}} articles this month. Favorites; Login; Register; View and print all favorites; Clear all your favorites; Meeting Resource Center; Abstract Number: 0403. JAK inhibitors have been approved for the treatment of rheumatoid arthritis (RA), and we know that they are fairly good with respect to the peripheral joints because of our experience with them in RA. “If we heed these lessons and implement change thoughtfully, rheumatology will enter a new era as an even more essential and highly sought-after specialty,” she said in her speech. There was also a slight dose response with the 12-mg dose being slightly better than the 6-mg dose, although the difference between the 2 doses did not reach statistical significance. These studies showed that ixekizumab and secukinumab were superior to adalimumab with regard to the skin, and both drugs were both noninferior to adalimumab with regard to the joints. We would like to show you a description here but the site won’t allow us. I might then consider the IL-12/23 inhibitor ustekinumab because that drug has been in the market for quite some time and it is a very good drug with respect to the skin, although in my experience it is not as good a drug as TNF inhibitors for the joints. Presented at: ACR Convergence 2020; November 5-9, 2020. In clinical practice, I believe that this distinction may not matter that much, as both TNF and IL-17 inhibitors would probably work on both conditions. Disclosure: Dr Atul A. Deodhar declared affiliations with the pharmaceutical industry. Presented at: ACR Convergence 2020; November 5-9, 2020. There are some really interesting poster and abstract presentations on spondyloarthritis at the ACR Convergence 2020. Mease P, Lertratanakul A, Strober B, et al. Information from the ACR presentations are under embargo until November 5, 2020 … Abstract 907. Michael B. Brenner, MD, was named an ACR Master, which recognizes “outstanding contributions to the ACR and the field of rheumatology through scholarly achievement and/or service to their patients, students, and profession.” In addition, Daniel Hal Solomon, MD, MPH, was given the Excellence in Investigative Mentoring Award, which honors “contributions to the rheumatology profession through outstanding and ongoing mentoring.”. Program and Faculty are updated daily - check back often for the most up-to-date information. All Days; Wed, Nov 4; Thu, Nov 5; Fri, Nov 6; Sat, Nov 7; Sun, Nov 8; Mon, Nov 9; Tue, Nov 10; Sat, Nov 21; Full Schedule - ACR Convergence 2020. There were several interesting abstracts presented at this year’s ACR annual meeting from a therapy standpoint, some of which were also presented at the 2020 European League Against Rheumatism (EULAR) annual meeting. Guselkumab, an interleukin (IL)-23 p19 inhibitor, has been effective in PsA, as demonstrated by the results of phase 2 and phase 3 studies published in the Lancet. However, one has to take this with a “pinch of salt” when one is looking at clinical trials that assess safety, as longer-term follow-up in postmarketing experience is needed. Ashvattha Therapeutics Selected to Present Virtual Poster at ACR Convergence 2020. Gravallese and Solomon lamented the inability to interact directly with fellow participants but noted an upside: About 16,400 people from 111 countries attended at least some portion of the conference, compared with the typical 9,000 to 10,000 attendees. One would also take into account whether there is significant skin involvement, as we know that IL-17 and IL-23 inhibitors are superior to TNF inhibitors with respect to the skin. Home of the insider insights newsletter and the Canadian Insider Club which offers alerts and premium research. If a patient has not responded to treatment with 1 or more TNF inhibitors, then I would probably use IL-17 inhibitors first, only because they have a longer track record compared to the JAK inhibitors. ACR CONVERGENCE 2020—The field of rheumatology is vast, with innumerable diseases to consider in each differential and with myriad possible presentations of each condition. What was reported at the ACR 2020 meeting was the effect of guselkumab on axial disease in PsA. The tally included over 120 abstracts: two plenary presentations, 36 oral presentations, one late-breaking poster and 86 poster … Pages: 1-4231; First Published: 09 November 2020; Abstract; PDF; Request permissions; Tools. Type here to filter the list. Coates L, Gladman D, Van de Bosch F, et al. Abstract 907. Favorites; Login; Register; View and print all favorites; Clear all your favorites; Meeting Resource Center; ACR Convergence 2020 . Norwood, MA, Oct. 21, 2020 (GLOBE NEWSWIRE) -- Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (“Corbus” or the “Company”), a clinical-stage drug development company pioneering transformative medicines that target the endocannabinoid system, today announced the presentation of three abstracts at the American College of Rheumatology (“ACR”) Convergence 2020 being held … The study concluded that there is a high burden of these needs among medically and psychosocially complex patients with lupus and that iCMP can successfully uncover and begin to address these barriers to care. It is very important to assess the patients’ status in terms of how comfortable they are with the route of administration (oral vs injection), their risk tolerance, their insurance, etc. In clinical practice, my decision will depend on how severe the patient’s musculoskeletal disease and skin disease are. 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